Isaac Pessah, Ph.D.

Research in the Pessah lab examines the molecular mechanism by which environmentally relevant chemical agents influence calcium-dependent signal transduction mechanisms in muscle and nerve cells. His research centers around the structure and function of a recently identified superfamily of SR/ER Ca2+ channels, the so-called ryanodine receptors and inositol 1,4,5-triphosphate receptors (IP3 receptors), which function as a major site of convergence for cellular signals involving Ca2+. Another major interest is the molecular mechanisms by which polychlorinated biphenyls (PCBs) and organochlorine (OC) insecticides alter cellular Ca2+ signaling in excitable and nonexcitable cells.

Email address: inpessah@ucdavis.edu

For more information on Dr. Pessah, refer to http://neuroscience2.ucdavis.edu/faculty/?IPessah