ETX 214 – Mechanisms of Toxicity

UC Davis

Spring 2006

 

Matthew Wood's Lectures

 

Lecture 1.  Oxygen Toxicity – You Can Stop Breathing Now.

 

            Lecture Notes (PDF file)

 

            Suggested Reading:

 

            1.  Free Radicals and Antioxidants Perspective

 

            2.  HIF, O2 & Proline Hydroxylation Review

 

            3.  Redox in Living Cells

 

Lecture 2.  Defense Against Oxidative Stress.

 

            Lecture Notes (PDF file)

 

            Suggested Reading

 

            1.  Peroxiredoxin Function

 

            2.  Sulfiredoxin Protein

 

Lecture 3.  Oxidative Stress. Perception, Signal Transduction & Gene Regulation.

 

            Lecture Notes (PDF file)

 

            Suggested Reading

 

            1.  Bacterial H2O2 Adaptation

 

Lecture 4.  Engine Degreasers, Dry Cleaning Solvents & Microorganisms

 

            Lecture Notes (PDF file)

 

            Suggested Reading

 

            1.  Redox Sensors

 

            2.  Bioremediation & Genomics