Environmental Toxicology Faculty

Barry Wilson Professor Department of Animal Science Department of Environmental Toxicology 4209 Meyer Hall Phone: (530) 752-3519 Email:bwwilson@ucdavis.edu

Research:

Barry Wilson was trained as a zoologist and general physiologist. He is interested in growth and neuromuscle development and over the years he has become more and more interested in chemicals that affect development and the nervous system. He has an appointment in both the Departments of Animal Science and Environmental Toxicology at UC Davis and an Adjunct appointment in Pharmacologu at the University of Mississippi in Oxford, MS.

Currently he is studying organophosphorus agents such as pesticides using experimental animals (chickens, quail, mice, fish) and humans. His research applies to agriculture, ecotoxicology and public health. In addition Wilson has been working with Dr Bill Lasley, UCD Vet Med. on biomarkers of reproductive state, specifically on antibodies to fecal testosterone to study the reproductive state of wild mice and birds. Specialties of Wilson's laboratory include: birds, neuromuscle defects and toxicology; cell and tissue culture growth, fundamental and applied research on acetylcholinesterase (AChE), one of the enzymes that regulates neural transmission and that is blocked by pesticides and several chemical warfare agents.

Recent projects include studies of runoff of agricultural chemical protectants from anti-ache, standardizing blood cholinesterase assays to monitor pesticide exposures, effects of pesticides on growth of embryo muscle and nerve cells, and pesticides and reproduction of mice and birds. He has been fortunate to work with colleagues that permit his studying from tree to sea, from molecule to ecosystem.

The long term goals of his studies are to sustain agriculture without damaging the environment, and to understand and preserve human and ecosystem health. Wilson's research has been supported by agricultural commodity groups, CalFed, California EPA, the NIH, US EPA and Department of Defense and, in the past, the Muscular Dystrophy Association of America.

Education:

• Zoology, UCLA, Los Angeles, CA, 1962 PhD
• Biology, Illinois Institute of Technology, Chicago Ill 1957 M.S.
• Biology, Illinois Institute Technology, Chicago, ILL, 1957 B.S.
• Liberal Arts, University of Chicago, Chicago, ILL, 1950 B.A.

Teaching:

• MCIP 200L - Cell and tissue culture
• ETX 240 - Ecotoxicology
• ABI 187 - Amimal Biology

Professional Activities:

• Past and Current Member of the EPA Science Advisory Board
• Several UC Davis Graduate Groups
• Associate Editor for the Bulletin of Environmental Contamination and Toxicology

Recent Publications:

Wilson BW 2001. Acetylcholinesterases in "Handbook of Pesticide Toxicology (2nd edition) ed R.E. Krieger. New York, Academic Press pp 967-985.

Hamm, J. T.; Wilson, B. W.; Hinton, D. E. 2001. Increasing uptake and bioactivation with development positively modulate diazinon toxicity in early life stage medaka (Oryzias latipes). Toxicol. Sci. (2001), 61(2), 304-313.

Millam, J. R.; Delwiche, M. J.; Craig-Veit, C. B.; Henderson, J. D.; Wilson, B. W. 2000. Noninvasive characterization of the effects of diazinon on pigeons. Bull. Environ. Contam. Toxicol. (2000), 64(4), 534-541.

Hoffmann, Walter E.; Solter, Philip F.; Wilson, Barry W.1999. Clinical enzymology. Clin. Chem. Lab. Anim. (2nd Ed.) 399-454.

Bakshi, Kulbir; Pang, Susan N. J.; Snyder, Robert; Abou-Donia, Mohamed B.; Albuquerque, Edson X.; Daniels, Jeffrey I.; Gardner, Donald E.; Gaylor, David W.; Henderson, Rogene F.; James, John T.; Leffingwell, Sanford S.; Saady, Joseph J.; Spencer, Peter S.; Wagner, Bernard M.; Wilson, Barry W. 2000. Review of the U.S. Army's health risk assessments for oral exposure to six chemical-warfare agents. J. Toxicol. Environ. Health, Part A 59(5-6), 281-526.

Wilson, Barry W.; Henderson, John D.; Spencer, Peter S. 1998. Clinical effects of low-level exposures to chemical warfare agents in mice and chickens. Drug Chem. Toxicol. 21(Suppl. 1), 183-190.